Erythrocytosis has been reported as a possible effect of testosterone, which could be useful in patients with anemia. The best danger of erythrocytosis happens with injectable types of testosterone compared with transdermal preparations, particularly in supraphysiologic doses. An increase of as a lot as 44% of the baseline hematocrit has been reported .
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Rhoden EL, Morgentaler A. Risks of testosterone-replacement remedy and suggestions for monitoring. Testosterone replacement in hypogonadal men with angina improves ischaemic threshold and quality soda cams of life. Ajayi AAL, Mathur R, Halushka PV. Testosterone enhance human platelet thromboxane A2 receptor density and aggregation responses.
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We report a case of an acute ST-segment elevation myocardial infarction in a patient with conventional cardiac danger factors using supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this affected person additionally had polycythemia, likely secondary to high-dose testosterone. The patient underwent profitable percutaneous intervention of the proper coronary artery. Physicians and patients ought to pay consideration to the medical penalties of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996).
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